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CHAC1 Polyclonal Antibody
货号：YBAP11243 |
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规格： 50ul/100ul/200ul |
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价格： 980/1280/1890 |
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| Immunogen： | Recombinant protein of human CHAC1 | ||
Synonym: |
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| Calculated MW: | |||
| Observed MW: | |||
Source: |
Rabbit | ||
Isotype: |
IgG | Reactivity: H,M,R; Clonality: Polyclonal  |
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Application: |
ELISA IHC | ||
Purify: |
Affinity purification | ||
Concentration: |
1.7mg/ml | ||
Storage Buffer: |
PBS with 0.05% sodium azide, 50% glycerol, pH7.3 | ||
Storage: |
Store at -20℃. Avoid freeze / thaw cycles. |
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| Immunohistochemistry of Human liver cancer using CHAC1 Polyclonal Antibody at dilution of 1:40 |
Protocols： |
Buffer-Formulation WB-Guide IHC-Guide IP-Guide IF-Guide |
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Background: |
CHAC1 (ChaC, cation transport regulator homolog 1 (E. coli)) is a 264 amino acid cytoplasmic protein that belongs to the ChaC family. Induced by chemical activators of the unfolded protein response (UPR) pathway, including DTT, tunicamycin and thapsigargin, CHAC1 is a pro-apoptotic member of this pathway and may mediate the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade. Overexpression of CHAC1 may lead to an increase in apoptosis, while suppression of CHAC1 results in subdued apoptosis.
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