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KPNA2 Polyclonal Antibody
QIP2; RCH1; IPOA1; SRP1alpha
货号:YBAP11955
价格: 980/1280/1890
Immunogen: Recombinant protein of human KPNA2
Synonym:
QIP2; RCH1; IPOA1; SRP1alpha
Calculated MW: 58kDa
Observed MW: Refer to figures
Source:
Rabbit
Isotype:
IgG
Reactivity: H,M,R;

Clonality: Polyclonal


Application:
WB
Purify:
Affinity purification
Concentration:
5.67mg/ml
Storage Buffer:
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
KPNA2 Polyclonal Antibody


Western blot analysis of MCF7, U937, PC-3 and U251 cel, mouse testis and liver tissue, using KPNA2 Polyclonal Antibody at dilution of 1:500

Protocols:
Buffer-Formulation WB-Guide IHC-Guide IP-Guide IF-Guide
Background:
The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination.

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