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VASP (Ab-157) Polyclonal Antibody
货号:YBAP12268 |
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规格: 50ul/100ul/200ul |
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价格: 980/1280/1890 |
Immunogen: | Synthetic peptide of human VASP (Ab-157) | ||
Synonym: |
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Calculated MW: | 40kDa | ||
Observed MW: | Refer to figures | ||
Source: |
Rabbit |
Isotype: |
IgG | ||
Application: |
WB IF | ||
Purify: |
Affinity purification | ||
Concentration: |
1mg/ml | ||
Storage Buffer: |
PBS with 0.05% sodium azide, 50% glycerol, pH7.3 | ||
Storage: |
Store at -20℃. Avoid freeze / thaw cycles. |
Western blot analysis of 293 and C6 cells , using VASP (Ab-157) Polyclonal Antibody at dilution of 1:500 |
Protocols: |
Buffer-Formulation WB-Guide IHC-Guide IP-Guide IF-Guide |
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Background: |
Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
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