

工作时间 :
周一~~周五
9:00 -18:00
在非工作时间,您可以通过邮件订购产品,订购时请写明详细联系方式,谢谢支持!
销售:18321282235
技术:021-60514606
传真:021-37680378
顾经理微信 扫一扫,关注我们
JAK1 (Ab-1022) Polyclonal Antibody
JTK3; JAK1A; JAK1B
货号:YBAP12244 |
|
![]() |
|
规格: 50ul/100ul/200ul |
|
价格: 980/1280/1890 |
Immunogen: | Synthetic peptide of human JAK1 (Ab-1022) | ||
Synonym: |
JTK3; JAK1A; JAK1B | ||
Calculated MW: | 133kDa | ||
Observed MW: | Refer to figures | ||
Source: |
Rabbit |
Isotype: |
IgG | ||
Application: |
WB IHC | ||
Purify: |
Affinity purification | ||
Concentration: |
1mg/ml | ||
Storage Buffer: |
PBS with 0.05% sodium azide, 50% glycerol, pH7.3 | ||
Storage: |
Store at -20℃. Avoid freeze / thaw cycles. |
Western blot analysis of NIH/3T3, HepG2, HT29 and MDA cells , using JAK1 (Ab-1022) Polyclonal Antibody at dilution of 1:500 |
Protocols: |
Buffer-Formulation WB-Guide IHC-Guide IP-Guide IF-Guide |
||
Background: |
Janus kinase 1 (JAK1), is a member of a new class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The second phosphotransferase domain bears all the hallmarks of a protein kinase, although its structure differs significantly from that of the PTK and threonine/serine kinase family members. JAK1 is a large, widely expressed membrane-associated phosphoprotein. JAK1 is involved in the interferon-alpha/beta and -gamma signal transduction pathways. The reciprocal interdependence between JAK1 and TYK2 activities in the interferon-alpha pathway, and between JAK1 and JAK2 in the interferon-gamma pathway, may reflect a requirement for these kinases in the correct assembly of interferon receptor complexes. These kinases couple cytokine ligand binding to tyrosine phosphorylation of various known signaling proteins and of a unique family of transcription factors termed the signal transducers and activators of transcription, or STATs.
|
部门 |
姓名 | 手机 | |||
销售部 | 顾先生 | 1916510334@qq.com | 18321282235 | 1916510334 | |
技术部 | 技术支持 | 1781364813@qq.com | 13816899465 | 1781364813 |
全国免费电话:18321282235
销售: 18321282235
86-21-60514606
技术: 13816899465
传真: 021-37680378
The latest products