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PPP1CA Polyclonal Antibody
PPP1CA; MGC15877; MGC1674; PP-1A; PP1alpha; PPP1A
货号：YBAP12049 |
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规格： 50ul/100ul/200ul |
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价格： 980/1280/1890 |
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| Immunogen： | Recombinant protein of human PPP1CA | ||
Synonym: |
PPP1CA; MGC15877; MGC1674; PP-1A; PP1alpha; PPP1A | ||
| Calculated MW: | 38kDa | ||
| Observed MW: | Refer to figures | ||
Source: |
Rabbit | ||
Isotype: |
IgG | Reactivity: H,M,R; Clonality: Polyclonal  |
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Application: |
WB | ||
Purify: |
Affinity purification | ||
Concentration: |
1.66mg/ml | ||
Storage Buffer: |
PBS with 0.05% sodium azide, 50% glycerol, pH7.3 | ||
Storage: |
Store at -20℃. Avoid freeze / thaw cycles. |
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| Western blot analysis of HeLa cell, using PPP1CA Polyclonal Antibody at dilution of 1:500 |
Protocols： |
Buffer-Formulation WB-Guide IHC-Guide IP-Guide IF-Guide |
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Background: |
Type 1 protein phosphatase (PP1), a serine/threonine phosphatase, is highly conserved in eukaryotic cells. Four isoforms of PP1 have been characterized: PP1α, PP1δ, PP1γ1 and PP1γ2. Involvement in cell cycle regulation is one of the biological functions of PP1. It has been illustrated that PP1 dephosphorylates Rb and cdc25 during mitosis. A cell cycle-dependent phosphorylation at Thr320 of PP1α by cdc2 kinase inhibits PP1α activity.
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