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PRKDC (Ab-2609) Polyclonal Antibody
HYRC; p350; DNAPK; DNPK1; HYRC1; XRCC7; DNA-PKcs
货号：YBAP12261 |
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规格： 50ul/100ul/200ul |
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价格： 980/1280/1890 |
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| Immunogen： | Synthetic peptide of human PRKDC (Ab-2609) | ||
Synonym: |
HYRC; p350; DNAPK; DNPK1; HYRC1; XRCC7; DNA-PKcs | ||
| Calculated MW: | 469kDa | ||
| Observed MW: | Refer to figures | ||
Source: |
Rabbit | ||
Isotype: |
IgG | Reactivity: H; Clonality: Polyclonal  |
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Application: |
WB | ||
Purify: |
Affinity purification | ||
Concentration: |
1mg/ml | ||
Storage Buffer: |
PBS with 0.05% sodium azide, 50% glycerol, pH7.3 | ||
Storage: |
Store at -20℃. Avoid freeze / thaw cycles. |
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| Western blot analysis of HT29 and HepG2 cells , using PRKDC (Ab-2609) Polyclonal Antibody at dilution of 1:500 |
Protocols： |
Buffer-Formulation WB-Guide IHC-Guide IP-Guide IF-Guide |
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Background: |
The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties
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