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FBLN5 Polyclonal Antibody
EVEC, UP50, ADCL2, ARMD3, DANCE, ARCL1A, FIBL-5
货号:YBAP12594 |
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规格: 50ul/100ul/200ul |
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价格: 980/1280/1890 |
Immunogen: | Synthetic peptide of human FBLN5 | ||
Synonym: |
EVEC, UP50, ADCL2, ARMD3, DANCE, ARCL1A, FIBL-5 | ||
Calculated MW: | |||
Observed MW: | |||
Source: |
Rabbit |
Isotype: |
IgG | ||
Application: |
ELISA IHC | ||
Purify: |
Affinity purification | ||
Concentration: |
3.1mg/ml | ||
Storage Buffer: |
PBS with 0.05% sodium azide, 50% glycerol, pH7.3 | ||
Storage: |
Store at -20℃. Avoid freeze / thaw cycles. |
Immunohistochemistry of Human lung cancer using FBLN5 Polyclonal Antibody at dilution of 1:85 |
Protocols: |
Buffer-Formulation WB-Guide IHC-Guide IP-Guide IF-Guide |
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Background: |
The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).
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