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KPNB1 Polyclonal Antibody
IMB1; IPO1; IPOB; Impnb; NTF97
货号:YBAP13583 |
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规格: 50ul/100ul/200ul |
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价格: 980/1280/1890 |
Immunogen: | Synthetic peptide of human KPNB1 | ||
Synonym: |
IMB1; IPO1; IPOB; Impnb; NTF97 | ||
Calculated MW: | |||
Observed MW: | |||
Source: |
Rabbit |
Isotype: |
IgG | ||
Application: |
ELISA IHC | ||
Purify: |
Affinity purification | ||
Concentration: |
2.6mg/ml | ||
Storage Buffer: |
PBS with 0.05% sodium azide, 50% glycerol, pH7.3 | ||
Storage: |
Store at -20℃. Avoid freeze / thaw cycles. |
Immunohistochemistry of Human thyroid cancer using KPNB1 Polyclonal Antibody at dilution of 1:40 |
Protocols: |
Buffer-Formulation WB-Guide IHC-Guide IP-Guide IF-Guide |
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Background: |
Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore.
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